The Value of Haplotyping
Keywords:
haplotypeAbstract
The relevant unit of inheritance is not the allele but the ancestral haplotype. These sequences are inherited faithfully over thousands of generations. We have developed haplospecific markers for a region of Bota Chromosome 19 which influences fat metabolism. Haplotypes were identified by family segregation. Comparing haplotype frequencies between Wagyu, Angus and Simmental reveals breed specific ancestral haplotypes which allow the majority of Wagyu to be distinguished from Angus masquerading as Wagyu. Breed specific haplotypes are associated with traits characteristic of a breed. These haplotypes can then be used for marker assisted selection to increase favorable characteristics within a breed or to blend desired characteristics from different breeds.Downloads
Published
2013-11-13
Issue
Section
Articles
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
